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Cosmetic ingredients Skin microbiome improvement ingredient Biotilis

Skin microbiome, promotion of antimicrobial peptide production, anti-inflammatory effects, barrier function recovery effects, enhancement of tight junction barrier function.

BIOTILYS enhances the expression of antimicrobial peptides, improving antibacterial activity, anti-inflammatory effects, barrier function recovery, and the diversity of the skin microbiome. <Effects of Antimicrobial Peptides> - Antimicrobial peptides have a broad range of antibacterial activity and have been reported to exhibit antibacterial activity against Gram-positive Staphylococcus aureus, Gram-negative Pseudomonas aeruginosa, and even drug-resistant bacteria. - They have also been confirmed to improve tight junction barrier function and have anti-inflammatory effects on the skin, showing promise for the treatment of atopic dermatitis and psoriasis. <Stimuli for Antimicrobial Peptide Expression> - β-defensin 2 (hBD2): +229% - β-defensin 3 (hBD3): +19% - S100A7 (soriacin): +237% <Anti-inflammatory> - Toll-like receptor 2 (TLR2): -57% - IL-8: -58% <In Vivo: Barrier Function Recovery Effects> - Water vapor loss: -31% (after 6 hours) - Moisturizing function: +27% (after 3 hours) - Improvement in the diversity of the skin microbiome

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  • Other medical supplies and cosmetic manufacturing materials
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Cosmetic Ingredient: Hair Prose <Hawthorn>

Extend, grow. By suppressing the transition from the growth phase to the regression phase, maintain hair density.

This document is a technical report explaining 'Hairproze <Hawthorn>', which is expected to prevent thinning hair through the extension of the growth phase. It includes information on "shortening of the growth phase due to disruption of the hair cycle" and "product information." Additionally, it introduces various testing methods and results, including "hair growth effects (human volunteer trials)." We encourage you to read it. 【Contents (excerpt)】 ■ Shortening of the growth phase due to disruption of the hair cycle ■ Suppression of transition to the regression phase ■ Product information ■ Suppression of FGF-5 expression related to the hair cycle ■ Countermeasures for androgenetic alopecia *More detailed information on ingredients and consumer survey results is available on the Maruzen Pharmaceutical official website. Please check the link below for more information.

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  • Other pharmaceutical intermediates and cosmetic ingredients
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Ginkgo flavonoids for cosmetics, an antioxidant and circulation-promoting ingredient derived from ginkgo leaves.

Enhance circulation with the power of ginkgo leaves. A plant ingredient for anti-aging care that combines blood circulation promotion, antioxidant, and anti-inflammatory properties.

Ginkgo flavonoids are cosmetic ingredients extracted and refined from carefully selected ginkgo leaves (Ginkgo biloba). They contain a high concentration of flavonol glycosides and terpene lactones unique to ginkgo leaves, excelling in promoting blood circulation, antioxidant effects, and anti-inflammatory properties, making them widely applicable in anti-aging and sensitive skin products. The main components, quercetin, kaempferol, and isorhamnetin derivatives, remove free radicals and alleviate damage caused by oxidative stress. At the same time, they promote peripheral blood flow and address dullness and lack of firmness in the skin. Key functional features: ✅ Promotes blood circulation (supports circulation in peripheral capillaries) ✅ Powerful antioxidant effects (suppresses aging factors) ✅ Anti-inflammatory effects (relieves redness and skin roughness) ✅ Care for light stress from UV rays and blue light ✅ Supports skin firmness and brightness Derived from natural sources, it is also ideal for fragrance-free formulations and clean beauty products.

  • Cosmetic materials and raw materials
  • Promote raw materials

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